Some Basic Concepts of Chemistry · NCERT Class 11
- Number of moles: n = m / M, where m is mass in grams, M is molar mass in g mol⁻¹.
- Number of particles: N = n × Nₐ, with Nₐ = 6.022 × 10²³ mol⁻¹.
- Molar volume of an ideal gas at STP (0 °C, 1 bar): 22.7 L mol⁻¹ (or 22.4 L mol⁻¹ at older STP of 1 atm).
- Percentage composition: (mass of element in 1 mol / molar mass of compound) × 100.
- Molarity (M): moles of solute per litre of solution, unit mol L⁻¹.
- Molality (m): moles of solute per kilogram of solvent, unit mol kg⁻¹.
- Mass percent: (mass of solute / mass of solution) × 100.
- Significant figures rule for multiplication/division: Result keeps as many significant figures as the quantity with the fewest.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Structure of Atom · NCERT Class 11
- Formula or fact: c = νλ · Meaning: Speed of light equals frequency times wavelength.
- Formula or fact: E = hν = hc/λ · Meaning: Energy of a photon depends on its frequency.
- Formula or fact: λ = h/mv · Meaning: de Broglie wavelength of a particle with mass m and velocity v.
- Formula or fact: Δx × Δp ≥ h/4π · Meaning: Heisenberg uncertainty relation for position and momentum.
- Formula or fact: Eₙ = −13.6/n² eV · Meaning: Energy of an electron in the nth orbit of hydrogen (Bohr model).
- Formula or fact: rₙ = 0.529 × n² Å · Meaning: Radius of nth Bohr orbit for hydrogen.
- Formula or fact: Aufbau principle · Meaning: Electrons fill orbitals in order of increasing energy: 1s, 2s, 2p, 3s, 3p, 4s, 3d, 4p, …
- Formula or fact: Pauli exclusion principle · Meaning: No two electrons in an atom can have the same set of all four quantum numbers.
- Formula or fact: Hund's rule · Meaning: Electrons occupy degenerate orbitals singly first, with parallel spins, before pairing.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Classification of Elements and Periodicity in Properties · NCERT Class 11
- Effective nuclear charge (Z_eff): Z_eff = Z − σ, where Z is atomic number and σ is shielding constant. It measures the net positive charge felt by a valence electron.
- Ionisation enthalpy (Δ_i H): Minimum energy required to remove the most loosely bound electron from an isolated gaseous atom in its ground state. Unit: kJ mol⁻¹.
- Electron gain enthalpy (Δ_eg H): Enthalpy change when an electron is added to an isolated gaseous atom. A negative value means energy is released.
- Electronegativity: A measure of an atom's ability to attract shared electrons in a covalent bond. Pauling scale is commonly used; fluorine = 4.0.
- Covalent radius: Half the distance between nuclei of two identical atoms bonded covalently.
- Periods and blocks: Period 1 has 2 elements (1s); periods 2 and 3 have 8 elements each (s and p blocks); period 4 has 18 elements (s, p and d blocks).
- Diagonal relationship: Certain pairs (Li–Mg, Be–Al, B–Si) show similar properties because the increase in nuclear charge across a period offsets the increase in size down a group.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Chemical Bonding and Molecular Structure · NCERT Class 11
- Bond order (MOT) = (Nb − Na) / 2, where Nb = electrons in bonding MOs, Na = electrons in antibonding MOs. Higher bond order means stronger, shorter bond.
- Formal charge = Valence electrons of free atom − [Non-bonding electrons + ½(Bonding electrons)].
- Dipole moment μ = q × d, where q is charge magnitude and d is separation distance. SI unit is coulomb-metre; often given in debye (1 D ≈ 3.336 × 10⁻³⁰ C·m).
- Hybridisation and geometry:
- sp → linear, 180° (BeCl₂, CO₂)
- sp² → trigonal planar, 120° (BF₃, C₂H₄)
- sp³ → tetrahedral, 109.5° (CH₄, NH₄⁺)
- sp³d → trigonal bipyramidal, 90° and 120° (PCl₅)
- sp³d² → octahedral, 90° (SF₆)
- VSEPR repulsion order: Lone pair–lone pair > lone pair–bond pair > bond pair–bond pair.
- Sigma (σ) bond: Formed by head-on overlap of orbitals along the internuclear axis.
- Pi (π) bond: Formed by sideways overlap of p orbitals above and below the internuclear axis.
- Resonance: When a single Lewis structure cannot represent actual electron distribution, we draw multiple structures; the real molecule is a hybrid.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Equilibrium · NCERT Class 11
- Kc = [products]^coefficients / [reactants]^coefficients (each concentration in mol L⁻¹).
- Kp = Kc (RT)^Δn, with Δn = sum of gaseous product coefficients minus sum of gaseous reactant coefficients.
- pH = −log₁₀[H⁺]; pOH = −log₁₀[OH⁻]; pH + pOH = 14 (at 25 °C).
- Kw = [H⁺][OH⁻] = 1.0 × 10⁻¹⁴ at 25 °C.
- For a weak acid HA with dissociation constant Ka, degree of dissociation α ≈ √(Ka / C) when α is small.
- Henderson–Hasselbalch equation for a buffer: pH = pKa + log₁₀([salt]/[acid]).
- Ksp for AgCl ⇌ Ag⁺ + Cl⁻ is Ksp = [Ag⁺][Cl⁻]; precipitation begins when ionic product > Ksp.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Organic Chemistry – Some Basic Principles and Techniques · NCERT Class 11
- General formula of alkanes: CₙH₂ₙ₊₂ (saturated hydrocarbons with only single bonds).
- General formula of alkenes: CₙH₂ₙ (one carbon–carbon double bond).
- General formula of alkynes: CₙH₂ₙ₋₂ (one carbon–carbon triple bond).
- Degree of unsaturation (DBE): (2C + 2 + N − H − X) / 2, where C = carbons, N = nitrogens, H = hydrogens, X = halogens; counts rings plus multiple bonds.
- Rf value in chromatography: Rf = (distance moved by substance) / (distance moved by solvent front); a characteristic ratio used to identify compounds.
- Boiling-point trend: In a homologous series, boiling point rises by roughly 20–30 °C for each added –CH₂– unit because of increasing molecular mass and surface area.
- Electronegativity order affecting polarity: F > O > N > C; bonds to more electronegative atoms are polar and influence solubility and reactivity.
- Inductive effect: Electron-withdrawing groups (–NO₂, –Cl) pull electron density through sigma bonds; electron-donating groups (–CH₃) push electron density; both affect acidity and basicity.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Hydrocarbons · NCERT Class 11
- Alkane general formula: CₙH₂ₙ₊₂. Each successive member differs by CH₂ (homologous series).
- Degree of unsaturation (DBE): For CₓHᵧ, DBE = (2x + 2 − y) / 2. One double bond or one ring equals one DBE; one triple bond equals two.
- Markovnikov's rule: In the addition of HX to an unsymmetrical alkene, H goes to the carbon with more H atoms; the halide goes to the carbon with fewer H atoms.
- Anti-Markovnikov (peroxide effect): With HBr in the presence of peroxides, the opposite orientation occurs via a free-radical mechanism. HCl and HI do not show this effect.
- Benzene resonance energy: Benzene is about 150 kJ mol⁻¹ more stable than a hypothetical "cyclohexatriene" with localised double bonds. This extra stability explains its preference for substitution over addition.
- Hückel's rule for aromaticity: A planar, cyclic, fully conjugated system is aromatic if it has (4n + 2) π electrons (n = 0, 1, 2, …).
- Combustion of hydrocarbons: Complete combustion gives CO₂ and H₂O. Example: CH₄ + 2 O₂ → CO₂ + 2 H₂O.
- Ozonolysis: Alkenes react with ozone followed by zinc/water to cleave the double bond and yield aldehydes or ketones; useful for locating the double bond position.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
The d-and f-Block Elements · NCERT Class 12
- General electronic configuration of d-block: (n−1)d¹⁻¹⁰ ns¹⁻². For the first transition series (Sc to Zn), n = 4.
- Exceptional configurations: Chromium is [Ar] 3d⁵ 4s¹ and copper is [Ar] 3d¹⁰ 4s¹ owing to the extra stability of half-filled and fully filled d-orbitals.
- Oxidation state trend (first series): Maximum oxidation state increases from Sc (+3) to Mn (+7), then decreases towards Zn (+2). The +2 state arises from loss of two 4s electrons.
- Standard electrode potential: E° values become less negative across the series, meaning later elements are weaker reducing agents. Copper has a positive E° for Cu²⁺/Cu, so it does not liberate H₂ from dilute acids.
- Dichromate ion in acid: Cr₂O₇²⁻ + 14 H⁺ + 6 e⁻ → 2 Cr³⁺ + 7 H₂O. Orange dichromate is reduced to green Cr³⁺.
- Permanganate ion in acid: MnO₄⁻ + 8 H⁺ + 5 e⁻ → Mn²⁺ + 4 H₂O. Purple permanganate becomes nearly colourless Mn²⁺.
- Lanthanoid configuration: [Xe] 4f¹⁻¹⁴ 5d⁰⁻¹ 6s². The +3 state is most stable because removal of two 6s and one 4f or 5d electron gives a stable configuration.
- Actinoid configuration: [Rn] 5f¹⁻¹⁴ 6d⁰⁻¹ 7s². Uranium commonly shows +6 (as in UO₂²⁺).
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Alcohols, Phenols and Ethers · NCERT Class 12
- General formula of alcohols: CₙH₂ₙ₊₁OH (for saturated, mono-hydroxy alcohols).
- Acidity order: alcohols (pKₐ ≈ 16–18) < water (pKₐ ≈ 15.7) < phenol (pKₐ ≈ 10).
- Lucas test: tertiary alcohols react immediately with Lucas reagent (anhydrous ZnCl₂ + conc. HCl) giving a turbid layer; secondary alcohols react in 5–10 minutes; primary alcohols do not react at room temperature.
- Iodoform test: ethanol and any secondary alcohol with a CH₃–CHOH– unit give a yellow precipitate of CHI₃ when warmed with I₂ and NaOH.
- Kolbe reaction: phenol + NaOH → sodium phenoxide; then CO₂ at 400 K and 4–7 atm → sodium salicylate → salicylic acid on acidification.
- Reimer–Tiemann reaction: phenol + CHCl₃ + aqueous NaOH → salicylaldehyde (ortho-hydroxybenzaldehyde).
- Williamson synthesis: R–O⁻Na⁺ + R′–X → R–O–R′ + NaX (works best when R′–X is a primary halide to favour Sₙ2).
- Dehydration temperature guide: ethanol requires about 443 K with excess conc. H₂SO₄ to form ethene; at 413 K diethyl ether forms instead.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Amines · NCERT Class 12
- General formula of amines: Primary amine R–NH₂, secondary amine R₂NH, tertiary amine R₃N.
- IUPAC naming: Replace the ending -e of the parent alkane with -amine. Example: CH₃–NH₂ is methanamine; C₆H₅–NH₂ is aniline (common) or benzenamine (IUPAC).
- Basicity order in gas phase: (CH₃)₃N > (CH₃)₂NH > CH₃NH₂ > NH₃ (inductive effect dominates).
- Basicity in aqueous solution: (CH₃)₂NH > CH₃NH₂ > (CH₃)₃N > NH₃ (solvation effect also matters).
- Reduction of nitro compounds: R–NO₂ + 3H₂ (Ni catalyst, or Sn/HCl, or Fe/HCl) → R–NH₂ + 2H₂O.
- Gabriel synthesis: Potassium phthalimide + R–X → N-alkylphthalimide; then hydrolysis with aqueous NaOH or hydrazine gives R–NH₂.
- Hoffmann bromamide degradation: R–CO–NH₂ + Br₂ + 4NaOH → R–NH₂ + Na₂CO₃ + 2NaBr + 2H₂O (amine has one carbon less).
- Diazotisation: C₆H₅–NH₂ + NaNO₂ + 2HCl (0–5 °C) → C₆H₅–N₂⁺Cl⁻ + NaCl + 2H₂O.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →
Biomolecules · NCERT Class 12
- Glucose molecular formula: C₆H₁₂O₆ — an aldohexose with an aldehyde group at C-1.
- Fructose molecular formula: C₆H₁₂O₆ — a ketohexose with a ketone group at C-2.
- Peptide bond formation: amino acid 1 + amino acid 2 → dipeptide + H₂O (condensation reaction between –COOH of one and –NH₂ of another).
- Isoelectric point: the pH at which an amino acid exists as a zwitterion with no net charge.
- DNA double helix: two antiparallel strands held by hydrogen bonds; A pairs with T (two H-bonds), G pairs with C (three H-bonds).
- Reducing sugars: carbohydrates with a free aldehyde or ketone group that can reduce Fehling's solution or Tollens' reagent (e.g., glucose, maltose).
- Non-reducing sugars: sucrose is non-reducing because both anomeric carbons are involved in the glycosidic bond.
- Vitamin deficiency examples: Vitamin A deficiency causes night blindness; Vitamin C deficiency causes scurvy; Vitamin D deficiency causes rickets.
NEET UG topic notes and practice → · NCERT chapter on a page + mind map →